Kempston
Seresto Flea and Tick Control Collar for Small Dog up to 8kg

Seresto Flea and Tick Control Collar for Small Dog up to 8kg

32% OFF

£37.49

Regular Price: £55.00

In stock

  • Built in Collar safety release mechanism
  • Non-greasy & Water-resistant
  • Up to 8 months continuous protection against fleas and ticks
  • Kills fleas and repels and kills ticks
  • Odourless
- +

Description

Now available without a prescription, Seresto flea and tick collars protect your dog for up to 8 months in a single application. The Seresto collars can be used on puppies from 7 weeks.

The small collar is for Dogs under 8kg with a maximum neck size 36cm

Other Seresto collars are also available for dogs over 8Kg and cats 

Details

Brand Seresto
Pet Age Adult

Delivery

At Petwell we offer 2 types of products that have different shipping rates:

Regular Products

  • Orders over £29 of regular products receive FREE SHIPPING (*3-5 Days)
  • Orders under £29 incur a £2.99 shipping charge for Standard Shipping (*3-5 days)
  • Express Tracked (*1-3 Days) and Premium Tracked (*1 Day) shipping options available at checkout.
  • "Regular" products are highlighted blue on the basket page

 

Shipping Included Products

  • No shipping charges at checkout.
  • Not counted towards free shipping for "regular" products over £29
  • "Shipping included" products are easy to spot, they have an orange ‘Shipping Included’ sticker placed on the top of the product and are highlighted orange on the basket page.
  • Sent separately via Standard (*3-5 Day) shipping service

 

 *Estimated delivery time from when the order is despatched (orders are usually despatched within 1-2 working days)

 

CLICK TO SEE ALL SHIPPING RATES HERE

 

Highlands & Islands

Deliveries to the following locations and postcodes on orders over 2Kg incur a £4.99 courier charge. (there is no extra charge for UK mainland orders over 2Kg)

Premium tracked (1 day) delivery is not available

Channel Islands - GY, JE
Isle of Man – IM
Isles of Scilly – TR
Isle of Wight – PO
Northern Ireland - BT
Northern Scotland - AB, FK, IV, KW, PA, PH
Scottish Offshore Islands - HS, IV, KA, KW, PA, PH, ZE

 

Europe

Unfortunately, we cannot currently deliver outside of the British Isles

SPC

SUMMARY OF PRODUCT CHARACTERISTICS

 

 

1.      NAME OF THE VETERINARY MEDICINAL PRODUCT

 

Seresto Flea and Tick Control 1.25 g + 0.56 g, collar for small dogs ≤ 8 kg

 

2.      QUALITATIVE AND QUANTITATIVE COMPOSITION

 

Active substances:

 

One collar of 38 cm (12.5 g) contains 1.25 g imidacloprid and 0.56 g flumethrin as active substances.

 

Excipients:

 

For the full list of excipients, see section 6.1.

 

3.      PHARMACEUTICAL FORM

 

Collar

Grey, odour free collar.

 

4.         CLINICAL PARTICULARS

 

4.1       Target species

 

Dogs (≤ 8 kg)

 

4.2       Indications for use, specifying the target species

 

For the treatment (Ctenocephalides felis) and prevention of flea (Ctenocephalides felis, C. canis) infestation for 7 to 8 months.

Protects the animal’s immediate surroundings against flea larvae development for 8 months.

The product can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD), where this has been previously diagnosed by a veterinary surgeon.

 

The product has persistent acaricidal (killing) efficacy against tick infestations (Ixodes ricinus, Rhipicephalus sanguineus, Dermacentor reticulatus) and repellent (anti-feeding) efficacy against tick infestations (Ixodes ricinus, Rhipicephalus sanguineus) for 8 months. It is effective against larvae, nymphs and adult ticks.

Ticks already on the dog prior to treatment may not be killed within 48 hours after collar application and may remain attached and visible. Therefore, removal of ticks already on the dog at the time of application is recommended. If you are unsure how to safely remove ticks from your animal, seek professional guidance. The prevention of infestations with new ticks starts within two days after application of the collar.

 

The product provides indirect protection against the transmission of the pathogens Babesia canis vogeli and Ehrlichia canis from the tick vector Rhipicephalus sanguineus, thereby reducing the risk of canine babesiosis and canine ehrlichiosis for 7 months.

 

For treatment of biting/chewing lice (Trichodectes canis) infestation.

 

4.3       Contraindications

 

Do not treat puppies less than 7 weeks of age.

Do not use in case of hypersensitivity to the active substances or to any of the excipients.

 

4.4    Special warnings for each target species

 

Ticks will be killed and fall off the host within 24 to 48 hours after infestation without having had a blood meal, as a rule. An attachment of single ticks after treatment cannot be excluded. For this reason, a transmission of infectious diseases by ticks cannot be completely excluded if conditions are unfavourable.

Ideally, the collar should be applied before the beginning of the flea or tick season.

 

As with all long-term topical products, periods of excessive seasonal hair shedding may lead to transient slight reduction of efficacy by loss of hair-bound portions of the active ingredients. Replenishment from the collar starts immediately so that full efficacy will be re-established without any additional treatment or collar replacement.

For optimum control of flea problems in heavily infested households it may be necessary to treat the environment with a suitable insecticide.

 

The product is water resistant; it remains effective if the animal becomes wet. However, prolonged, intense exposure to water or extensive shampooing should be avoided as the duration of activity may be reduced. Studies show that monthly shampooing or water immersion does not significantly shorten the 8 months efficacy duration for ticks after redistribution of the active substances in the coat whereas the product’s flea efficacy gradually decreased, starting in the 5th month.

 

4.5       Special precautions for use

 

(i) Special precautions for use in animals

 

None.

 

(ii) Special precautions to be taken by the person administering the veterinary medicinal product to animals

 

Keep the bag with the collar in the outer packaging until ready to use.

Immediately dispose of any remnants or off‑cuts of the collar (see section 4.9).

Do not allow children to play with the collar, or to put it into their mouths.

Imidacloprid and flumethrin are continuously released from the collar onto the fur whilst the collar is being worn.

The product may cause hypersensitivity reactions in some people.  People with known hypersensitivity (allergy) to the ingredients of the collar should avoid contact with the product.

The product may cause skin, eye and respiratory irritation in some people in very rare cases.  Pets wearing the collar should not be allowed to sleep in the same bed as their owners, especially children.

Wash hands with cold water after fitting the collar.

 

4.6    Adverse reactions (frequency and seriousness)

 

In rare cases mild behavioural disorders that may include scratching at the application site may be observed in animals that are not used to wearing collars on the first few days after fitting. Ensure that the collar is not fitted too tightly.

Mild application site reactions such as pruritus (itchiness), erythema (redness) and hair loss may occur. These have been reported as rare and usually resolve within 1 to 2 weeks without the need for collar removal. In single cases, a temporary collar removal may be recommended until the symptoms have disappeared.

In rare cases neurological symptoms as ataxia, convulsions and tremor may occur. In these cases collar removal is recommended.

Also in rare cases in dogs, slight and transient reactions such as depression, change of food intake, salivation, vomiting and diarrhoea might occur initially.

In very rare cases, application site reactions such as dermatitis, inflammation, eczema or lesions may occur and in these instances, collar removal is recommended.

 

The frequency of adverse reactions is defined using the following convention:

very common (affects more than 1 animal in 10)

common (affects 1 to 10 animals in 100)

uncommon (affects 1 to 10 animals in 1,000)

rare (affects 1 to 10 animals in 10,000)

very rare (affects less than 1 animals in 10,000)

 

4.7    Use during pregnancy, lactation or lay

 

Laboratory studies with either flumethrin or imidacloprid in rats and rabbits have not produced any effects on fertility or reproduction and showed no teratogenic, or foetotoxic effects. However, the safety of the veterinary medicinal product has not been established in target animals during pregnancy and lactation and in the absence of available data, the product is therefore not recommended in pregnant and lactating bitches.

 

4.8    Interaction with other medicinal products and other forms of interaction

 

None known.

 

4.9       Amounts to be administered and administration route

 

Cutaneous use. One collar per animal to be fastened around the neck.

Small dogs up to 8 kg body weight receive one collar of 38 cm length.

Dogs above 8 kg receive one collar for dogs > 8 kg of 70 cm length.

For external use only.

 

Remove collar from protective bag directly before use. Unroll collar and make sure that there are no remnants from the plastic connectors inside the collar. Adjust the collar around the animal's neck without tightening it too tight (as a guide, it should be possible to insert 2 fingers between the collar and the neck). Pull excess collar through the loop and cut off any excess length extending beyond 2 cm.

The collar should be worn continuously for the 8 month protection period and should be removed after the treatment period. Check periodically and adjust fit if necessary, especially when puppies are rapidly growing.

 

4.10  Overdose (symptoms, emergency procedures, antidotes), if necessary

 

Due to the nature of the collar overdosage is unlikely and signs of overdosage are not to be expected.

An overdosage of 5 collars around the neck was investigated in adult dogs for an 8 month period and in 7 week old puppies for a 6 month period and no adverse effects were observed besides slight hair loss and mild skin reactions.

In the unlikely event of the animal eating the collar mild gastrointestinal symptoms (e.g. loose stool) may occur.

 

4.11  Withdrawal period(s)

 

Not applicable.

 

5.      PHARMACOLOGICAL PROPERTIES

 

Pharmacotherapeutic group: ectoparasiticides, insecticides and repellents, pyrethrins and pyrethroids, Flumethrin combinations

ATCvet code: QP53AC55

 

5.1       Pharmacodynamic properties

 

Imidacloprid is an ectoparasiticide belonging to the chloronicotinyl group of compounds. Chemically, it can be classified as a chloronicotinyl nitroguanidine. Imidacloprid is active against larval flea stages, adult fleas and lice. Activity against C. felis starts immediately after application of the collar whereas adequate efficacy against C. canis starts within one week after application of the collar. In addition to the indications listed under section 4.2 an activity against Ctenocephalides canis and Pulex irritans fleas has been demonstrated.

Imidacloprid has a high affinity for the nicotinergic acetylcholine receptors in the post-synaptic region of the central nervous system (CNS) of the flea. The ensuing inhibition of cholinergic transmission in insects results in paralysis and death. Due to the weak nature of the interaction with mammalian nicotinergic receptors and the postulated poor penetration through the blood-brain barrier in mammals, it has virtually no effect on the mammalian CNS. Imidacloprid has minimal pharmacological activity in mammals.

Flumethrin is an ectoparasiticide of the synthetic pyrethroid group. According to current knowledge the synthetic pyrethroids interfere with the sodium channel of nerve cell membranes, resulting in a delay in repolarization of the nerve and finally killing of the parasite. In studies on structure-activity relationship of a number of pyrethroids interference with receptors of a certain chiral conformation was noted thereby causing a selective activity on ectoparasites. No anti-cholinesterase activity was noted with these compounds. Flumethrin is responsible for the product’s acaricidal activity and also prevents production of fertile eggs by its lethal effect on female ticks. In an in-vitro study 5 to 10 % of Rhipicephalus sanguineus ticks exposed to a sublethal dose of 4 mg flumethrin/L laid eggs which had a modified appearance (shrivelled, dull and dry) indicating a sterilising effect.

 

In addition to the tick species listed under section 4.2 activity has been demonstrated against Ixodes hexagonus, I. scapularis and the non-European tick species Dermacentor variabilis and the Australian paralysis tick I. holocyclus.

 

The product provides repellent (anti-feeding) activity against the claimed ticks, thus preventing repelled parasites from taking a blood meal and thereby indirectly aids in the reduction of the risk of Canine Vector-Borne Disease transmission.

 

In addition to the pathogens listed in section 4.2, indirect protection against the transmission of Babesia canis canis (by Dermacentor reticulatus ticks) has been shown in one laboratory study at day 28 after treatment, and indirect protection against the transmission of Anaplasma phagocytophilum (by Ixodes ricinus ticks) has been shown in one laboratory study at 2 months after treatment, thereby reducing the risk of diseases caused by these pathogens under the conditions of these studies.

 

Data of two clinical field studies performed in Leishmania infantum endemic areas indicate a significant reduction in the risk of Leishmania transmission by sand flies in treated dogs compared to non-treated dogs, while the efficacy of the product in the prevention of sandfly bites has not been established. The influence of shampooing or water immersion regarding the transmission of canine leishmaniosis has not been examined.

 

The collars were able to improve the Sarcoptes scabiei infestation in pre-infested dogs leading to a full cure after three months.

 

5.2    Pharmacokinetic particulars

 

Both active ingredients are slowly and continuously released in low concentrations from the polymer matrix system of the collar towards the animal. Both actives are present in the dog’s haircoat in acaricidal/insecticidal concentrations during the entire efficacy period. The active substances spread from the site of direct contact over the entire skin surface. Target animal overdose and serum kinetic studies have established that imidacloprid reached the systemic circulation transiently while flumethrin was mostly not measurable. Oral absorption of both active substances is not relevant for the clinical efficacy.

 


5.3    Environmental properties

 

See section 6.6.

 

6.      PHARMACEUTICAL PARTICULARS

 

6.1      List of excipients

 

Titanium dioxide (E 171)
Iron oxide black (E 172)

Dibutyladipate
Propylene glycol dicaprylocaprate

Epoxidised soybean oil
Stearic acid
Polyvinyl chloride

 

6.2    Major incompatibilities

 

None known.

 

6.3    Shelf life

 

Shelf-life of the veterinary medicinal product as packaged for sale: 5 years

 

6.4    Special precautions for storage

 

This veterinary medicinal product does not require any special storage conditions.

 

6.5    Nature and composition of immediate packaging

 

Box containing one single 38 cm polyvinyl chloride based collar packed into a PETP/PE bag.

 

6.6    Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products

 

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

This product should not enter water courses as it may be dangerous for fish and other aquatic organisms.

 

7.      MARKETING AUTHORISATION HOLDER

 

Bayer plc

400 South Oak Way

Green Park

Reading

Berkshire

RG2 6AD

 


8.         MARKETING AUTHORISATION NUMBER

 

Vm 00010/4218

 

9.         DATE OF FIRST AUTHORISATION

 

04 September 2017

 

10.       DATE OF REVISION OF THE TEXT

 

January 2019

 

 

 

Approved: 31 January 2019

 

 

 

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