FRONTLINE Plus Flea & Tick for Cats

Frontline Plus for Cats

In stock


  • NEW double action FRONTLINE PLUS protects your pet & home
  • KILLS FLEAS on your pet within 24 hours
  • KILLS TICKS on your pet within 48 hours
Product Name Price Qty
FRONTLINE Plus Flea & Tick Cat 3 pack

40% OFF


Regular Price: £24.99

FRONTLINE Plus Flea & Tick Cat 6 pack

36% OFF


Regular Price: £38.99



Frontline kills 98 to 100% of adult fleas within 24 hours of being administered and 48 within hours for lice. By breaking the life cycle of the parasite, you stop any future development on or around your pet. Frontline is effective for around 2 months against fleas and ticks for 1 month and so it is recommended that it be reapplied after 4 weeks.

Frontline is a simple and effective method for treating and preventing fleas and ticks, as well as controlling biting lice. Frontline’s active ingredient, Fipronil, is quickly absorbed into the oils of your pet’s skin and coat and within 24 hours is harmlessly dispersed throughout the body.

Frontline acts on the parasites directly rather than via your pet’s bloodstream so the parasites are not required to bite and therefore irritate and upset them further. Frontline is the longest lasting spot on flea treatment available without prescription because it continuously coats the skin of your pet for several weeks following application.

Frontline is an easy to apply treatment using the spot on method. Just snap off the top of the pipette and apply around the shoulder blades of your pet, parting the coat so the skin is visible. Squeeze the pipette and empty its contents on one or two spots where your pet is unable to lick it off.

Your pet should be at least 8 weeks old and 2 kg before being given Frontline.


Brand Frontline


At Petwell we offer 2 types of products that have different shipping rates:

Regular Products

  • Orders over £29 of regular products receive FREE SHIPPING (*3-5 Days)
  • Orders under £29 incur a £2.99 shipping charge for Standard Shipping (*3-5 days)
  • Express Tracked (*1-3 Days) and Premium Tracked (*1 Day) shipping options available at checkout.
  • "Regular" products are highlighted blue on the basket page


Shipping Included Products

  • No shipping charges at checkout.
  • Not counted towards free shipping for "regular" products over £29
  • "Shipping included" products are easy to spot, they have an orange ‘Shipping Included’ sticker placed on the top of the product and are highlighted orange on the basket page.
  • Sent separately via Standard (*3-5 Day) shipping service


 *Estimated delivery time from when the order is despatched (orders are usually despatched within 1-2 working days)




Highlands & Islands

Deliveries to the following locations and postcodes on orders over 2Kg incur a £4.99 courier charge. (there is no extra charge for UK mainland orders over 2Kg)

Premium tracked (1 day) delivery is not available

Channel Islands - GY, JE
Isle of Man – IM
Isles of Scilly – TR
Isle of Wight – PO
Northern Ireland - BT
Northern Scotland - AB, FK, IV, KW, PA, PH
Scottish Offshore Islands - HS, IV, KA, KW, PA, PH, ZE



Unfortunately, we cannot currently deliver outside of the British Isles


Frontline Plus Spot On Cat
Species:Cats, Ferrets
Therapeutic indication:Pharmaceuticals: Ectoparasiticides: For cats
Active ingredient:Fipronil, (S)-methoprene
Product:Frontline Plus Spot On Cat
Product index:Frontline Plus Spot On Cat
Qualitative and quantitative composition
Each pipette of 0.5 ml contains:
Active substances:
Fipronil 50.00 mg
(S)-methoprene 60.00 mg
Butylhydroxyanisole (E320) 0.10 mg
Butylhydroxytoluene (E321) 0.05 mg
For the full list of excipients, see below.
Pharmaceutical form
Spot-on solution. Clear amber solution
Clinical particulars
Target species
Cats and ferrets
Indications for use
In cats:
To be used against infestations with fleas, alone or in association with ticks and/or biting lice.
- Elimination of fleas (Ctenocephalides spp.). Insecticidal efficacy against new infestations with adult fleas persists for 4 weeks. Prevention of the multiplication of fleas by inhibiting the development of eggs (ovicidal activity), larvae and pupae (larvicidal activity) originating from eggs laid by adult fleas for six weeks after application.
- Elimination of ticks (Ixodes ricinusDermacentor variabilisRhipicephalus sanguineus). The product has a persistent acaricidal efficacy for up to 2 weeks against ticks (based on experimental data)
- Elimination of biting lice (Felicola subrostratus).
In ferrets:
To be used against infestations with fleas, alone or in association with ticks.
- Elimination of fleas (Ctenocephalides spp.). Insecticidal efficacy against new infestations with adult fleas persists for 4 weeks. Prevention of the multiplication of fleas by inhibiting the development of eggs (ovicidal activity), larvae and pupae (larvicidal activity) originating from eggs laid by adult fleas.
- Elimination of ticks (Ixodes ricinus). The product has a persistent acaricidal efficacy for 4 weeks against ticks (based on experimental data).
In the absence of available data, the product should not be used on kittens less than 8 weeks old and/or weighing less than 1 kg. The product should not be used on ferrets less than 6 months old.
Do not use on sick (e.g. systemic diseases, fever) or convalescent animals.
Do not use in rabbits, as adverse reactions with even mortality could occur. In absence of studies, the use of the product is not recommended in non-target species.
Do not use in case of hypersensitivity to the active substances or to any of the excipients.
Special warnings for each target species
Avoid the contact with the animal’s eyes. When treating infestations of parasites, all in-contact animals should be treated with an appropriate product at the same time.
Special precautions for use in animals
It is important to make sure that the product is applied to an area where the animal cannot lick it off and to make sure that animals do not lick each other following treatment. No data on the effect of bathing/shampooing on the efficacy of the product in cats and ferrets are available. However, based on information available for dogs shampooed as from 2 days after application of the product, it is not recommended to bath animals within 2 days after application of the product.
There may be an attachment of single ticks. For this reason a transmission of infectious diseases cannot be completely excluded if conditions are unfavourable.
Fleas from pets often infest the animal's basket, bedding and regular resting areas such as carpets and soft furnishings which should be treated, in case of massive infestation and at the beginning of the control measures, with a suitable insecticide and vacuumed regularly.
The potential toxicity of the product for kittens of less than 8 weeks of age in contact with a treated queen is not documented. Special care should be taken in this case.
Animals should be weighed accurately prior to treatment.
Special precautions to be taken by the person administering the product to animals
Keep pipettes in original packaging until ready to use.
This product can cause mucous membrane, skin and eye irritation. Therefore, contact of the product with mouth, skin and eyes should be avoided.
If the product is accidentally swallowed, seek medical advice immediately and show the package leaflet to the physician.
People with a known hypersensitivity (allergy) to insecticides or alcohol should avoid contact with the product. Avoid contents coming into contact with the fingers. If this occurs, wash hands with soap and water.
After accidental exposure the eye should be rinsed carefully with pure water.
Wash hands after use.
Treated animals should not be handled until the application site is dry, and children should not be allowed to play with treated animals until the application site is dry. It is therefore recommended that animals are not treated during the day, but should be treated during the early evening, and that recently treated animals are not allowed to sleep with owners, especially children.
Do not smoke, drink or eat during application.
Adverse reactions
Do not overdose.
Among the very rare suspected adverse reactions, transient skin reactions on the application site (scaling, local hair loss, itching, redness) and general itching or hair loss have been reported after use. Excessive salivation, reversible nervous signs (increased sensitivity to stimulation, depression, other nervous signs) or vomiting have also been observed after use. If licking occurs, a brief period of excessive salivation may be observed due mainly to the nature of the carrier.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Use during pregnancy, lactation or lay
The product can be used during pregnancy. For treatment during the lactating period, see “Special precautions for use in animals” section.
Laboratory studies in cats have not produced any evidence of teratogenic, foetotoxic or maternotoxic effects. The safety of the veterinary medicinal product has not been established in ferrets during pregnancy and lactation. Use only according to the risk-benefit assessment by the responsible veterinarian.
Do not use simultaneously with other flea products which are applied directly on to the animal.
Amounts to be administered and administration route
For external use only – Spot-on application.
One pipette of 0.5 ml per cat, corresponding to a minimum recommended dose of 5 mg/kg for fipronil and 6 mg/kg for (S)-methoprene, by topical application to the skin. In the absence of safety studies, the minimum treatment interval is 4 weeks.
One pipette of 0.5 mL per ferret corresponding to a dose of 50 mg for fipronil and 60 mg for (S)-methoprene per ferret, by topical application to the skin. The minimum treatment interval is 4 weeks.
The risk of experiencing adverse effects may increase with overdosing (see Adverse Reactions Section).
In cats
No undesirable effects were observed in target animal safety studies in cats and kittens aged 8 weeks and older and weighing about 1 kg treated once a month at five times the recommended dose for six consecutive months.
Itching may occur following treatment.
Overdose application of the product will cause a sticky appearance of hairs at the treatment spot. However, should this occur, it will disappear within 24 hours post application.
In ferrets
In ferrets aged 6 months and older and treated once every 2 weeks for four treatments, at five times the recommended dose, body weight loss was observed in some animals.
Pharmacological particulars
Pharmacotherapeutic group: Ectoparasiticides for topical use incl. insecticides QP53. The product is an insecticidal and acaricidal solution for topical use, containing an association of an adulticidal active ingredient, fipronil, in combination with an ovicidal and larvicidal active ingredient, (S)-methoprene.
Pharmacodynamic properties
Fipronil is an insecticide and acaricide belonging to the phenylpyrazole family. It acts by interacting with ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes. This results in uncontrolled activity of the central nervous system and death of insects or acarines. Fipronil kills fleas within 24 hours, ticks (Dermacentor variabilis, Rhipicephalus sanguineus, Ixodes scapularis, Ixodes ricinus, Haemaphysalis longicornis, Haemaphysalis flava, Haemaphysalis campanulata) and lice within 48 hours post-exposure.
(S)-Methoprene is an insect growth regulator (IGR) of the class of compounds known as juvenile hormone analogues that inhibit the development of immature stages of insects. This compound mimics the action of juvenile hormone and causes impaired development and death of the developing stages of fleas. The on-animal ovicidal activity of (S)-methoprene results from either direct penetration of the eggshell of newly laid eggs or from absorption through the cuticle of the adult fleas. (S)-methoprene is also effective in preventing flea larvae and pupae from developing, which prevents contamination of the environment of treated animals with the immature stages of fleas.
Pharmaceutical particulars
Butylhydroxyanisole (E320), Butylhydroxytoluene (E321), Ethanol, Polysorbate 80 (E433), Povidone, Diethylene glycol monoethyl ether
Major incompatibilities
None known.
Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 3 years
Special precautions for storage
Do not store above 30°C. Store in the original package.
Immediate packaging
Box of 1 or 2 blister card(s) of 3 x 0.5 ml pipettes with a scored tip. Blister card of 1 pipette.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements. Fipronil and (S)-methoprene may adversely affect aquatic organisms. Do not contaminate ponds, waterways or ditches with the product or empty containers.
Marketing Authorisation Number
Vm 08327/4267
Legal category
Legal category:NFA-VPS
GTIN description:Frontline Plus Spot On Cat x 3 pipettes
GTIN description:Frontline Plus Spot On Cat x 6 pipettes
GTIN description:Frontline Plus Spot On Cat x 1 pipette

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